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Trends Genet. 2000 Dec;16(12):544-51.

Form of the worm: genetics of epidermal morphogenesis in C. elegans.

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Dept of Biology, Sinsheimer Laboratories, University of California, Santa Cruz, CA 95064, USA.


The development of the epidermis of the nematode worm Caenorhabditis elegans illustrates many common processes of epithelial morphogenesis. In the worm, these morphogenetic movements have been described with single-cell resolution, and the roles of individual cells have been probed in laser killing experiments. Genetic dissection is yielding insights into the molecular mechanisms of these complex morphogenetic processes.

[Indexed for MEDLINE]

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