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J Affect Disord. 2000 Dec;61(1-2):95-9.

Early-onset versus late-onset atypical depression: unipolar and bipolar II.

Author information

1
Department of Psychiatry, Public Hospital "Morgagni", National Health Service, 47100, Forlì, Italy. f.benazzi@fo.nettuno.it

Abstract

BACKGROUND:

To find differences between early- and late-onset atypical depression (AD).

METHODS:

211 unipolar/bipolar II AD outpatients, interviewed with DSM-IV Structured Clinical Interview and depression rating scales. Logistic regression was used.

RESULTS:

Early-onset AD was significantly associated with age, female gender, duration of illness, recurrences, chronicity, MADRS, bipolar II and unipolar. Early-onset bipolar II AD was significantly associated with age, female gender, duration of illness, recurrences and chronicity. Early-onset unipolar AD was significantly associated with age.

LIMITATIONS:

Age at onset recall bias, single interviewer, non-blind, cross-sectional assessment, bipolar II diagnosis reliability.

CONCLUSIONS:

Bipolar II AD is more likely to be chronic if early onset.

PMID:
11099746
DOI:
10.1016/s0165-0327(99)00184-6
[Indexed for MEDLINE]

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