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Crit Care. 2000;4(5):269-81. Epub 2000 Sep 1.

Understanding gastrointestinal perfusion in critical care: so near, and yet so far.

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1
Centre for Anaesthesia, University College London, London, UK.

Abstract

An association between abnormal gastrointestinal perfusion and critical illness has been suggested for a number of years. Much of the data to support this idea comes from studies using gastric tonometry. Although an attractive technology, the interpretation of tonometry data is complex. Furthermore, current understanding of the physiology of gastrointestinal perfusion in health and disease is incomplete. This review considers critically the striking clinical data and basic physiological investigations that support a key role for gastrointestinal hypoperfusion in initiating and/or perpetuating critical disease.

PMID:
11094506
PMCID:
PMC137256
DOI:
10.1186/cc709
[Indexed for MEDLINE]
Free PMC Article
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