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Z Orthop Ihre Grenzgeb. 2000 Sep-Oct;138(5):425-9.

[Serum cobalt and serum chromium level in 2 patients with chronic renal failure after total hip prosthesis implantation with metal-metal gliding contact].

[Article in German]

Author information

1
Universitätsklinik für Orthopädie, AKH Wien. wolfram.brodner@akh-wien.ac.at

Abstract

PURPOSE:

The influence of chronic renal failure on serum cobalt and serum chromium in two patients with metal-on-metal bearing (Metasul) and cementless total hip arthroplasty (Alloclassic) is investigated.

METHODS:

Serum cobalt and serum chronium levels were determined in the postoperative course using atomic absorption spectrometry.

RESULTS:

Maximum values are found to be more than 100-fold elevated when compared to the reported median serum cobalt concentrations in patients with the same prosthesis type and no known renal disease.

CONCLUSION:

Chronic renal failure seems to be responsible for the marked elevation of serum cobalt and serum chromium.

CLINICAL RELEVANCE:

Despite evidence of adverse health reactions, a possible effect of long-term cobalt and chromium loading cannot be neglected. In our opinion, metal-on-metal bearings in THA should not be inserted in patients with chronic renal failure. Follow-up investigations (serum cobalt, serum chromium, serum creatinine, BUN, echocardiography) should be performed at short intervals.

PMID:
11084743
DOI:
10.1055/s-2000-10172
[Indexed for MEDLINE]
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