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Curr Microbiol. 2000 Dec;41(6):441-3.

The rpoN gene of Enterococcus faecalis directs sensitivity to subclass IIa bacteriocins.

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Laboratoire de Biologie Moléculaire, CNRS ESA 6031, IBMIG, Université de Poitiers, 40 avenue du recteur Pineau, 86022 Poitiers Cedex, France.


The final sigma 54 factor has been previously described to be involved in Listeria monocytogenes sensitivity to mesentericin Y105, a subclass IIa bacteriocin. Here, we identified the rpoN gene, encoding final sigma 54, of Enterococcus faecalis JH2-2 and showed that its interruption leads to E. faecalis resistance to different subclass IIa bacteriocins. Moreover, this rpoN mutant remained sensitive to nisin, a class I bacteriocin, suggesting that final sigma 54 is especially involved in sensitivity to subclass IIa bacteriocins.

[Indexed for MEDLINE]

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