Format

Send to

Choose Destination
Am J Ind Med. 2000 Dec;38(6):609-18.

Occupational risk factors for renal cell carcinoma in Montreal.

Author information

1
INRS-Institut Armand-Frappier, Laval, Quebec, Canada. marie-elise.parent@inrs-iaf.uquebec.ca

Abstract

BACKGROUND:

Little is known about the role of workplace exposures on the risk of renal cell cancer.

METHODS:

A population-based case-control study was undertaken in Montreal to assess the association between hundreds of occupational circumstances and several cancer sites, including the kidney. A total of 142 male patients with pathologically confirmed renal cell carcinoma, 1900 controls with cancer at other sites and 533 population-based controls were interviewed. Detailed job histories and relevant data on potential confounders were obtained. A group of chemists-hygienists evaluated each job reported and translated them into a history of occupational exposures using a checklist of 294 substances. Multivariate logistic regression models using either population, cancer controls, or a pool of both groups were used to estimate odds ratios.

RESULTS:

There were some indications of excess risks among printers, nursery workers (gardening), aircraft mechanics, farmers, and horticulturists, as well as in the following industries: printing-related services, defense services, wholesale trade, and retail trade. Notwithstanding the low precision of many of the odds ratio estimates, the following workplace exposures showed some evidence of excess risk: chromium compounds, chromium (VI) compounds, inorganic acid solutions, styrene-butadiene rubber, ozone, hydrogen sulphide, ultraviolet radiation, hair dust, felt dust, jet fuel engine emissions, jet fuel, aviation gasoline, phosphoric acid and inks.

CONCLUSIONS:

For most of these associations there exist no, or very little, previous data. Some associations provide suggestive evidence for further studies.

PMID:
11071683
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center