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Curr Biol. 2000 Oct 19;10(20):R739-41.

Dendritic cells: new roles for Cdc42 and Rac in antigen uptake?

Author information

1
MRC Laboratory for Molecular Cell Biology, University College London, UK. c.nobes@ucl.ac.uk

Abstract

In dendritic cells, macropinocytosis is downregulated during maturation and antigen presentation. New studies indicate a key role for Rho-family GTPases in this regulation, but what these proteins are actually doing remains a mystery.

PMID:
11069097
DOI:
10.1016/s0960-9822(00)00736-3
[Indexed for MEDLINE]
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