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J Am Acad Child Adolesc Psychiatry. 2000 Nov;39(11):1432-7.

Adoptive and biological families of children and adolescents with ADHD.

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Cognitive-Behavioral Therapy Program of the Psychiatry Service, Massachusetts General Hospital, Boston 02114, USA.



Using an adoption study design, the authors addressed the issue of genetics in attention-deficit hyperactivity disorder (ADHD).


This study examined the rates of ADHD and associated disorders in the first-degree adoptive relatives of 25 adopted probands with ADHD and compared them with those of the first-degree biological relatives of 101 nonadopted probands with ADHD and 50 nonadopted, non-ADHD control probands.


Six percent of the adoptive parents of adopted ADHD probands had ADHD compared with 18% of the biological parents of nonadopted ADHD probands and 3% of the biological parents of the control probands.


Results of this study lend support to the hypothesis that ADHD has a genetic component.

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