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Curr Opin Cell Biol. 2000 Dec;12(6):666-75.

Regulation of the meiotic cell cycle in oocytes.

Author information

1
European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117, Heidelberg, Germany. nebreda@EMBL-heidelberg.de

Abstract

The mitotic and meiotic cell cycle share many regulators, but there are also important differences between the two processes. The meiotic maturation of Xenopus oocytes has proved useful for understanding the regulation of Cdc2-cyclin-B, a key activator of G2/M progression. New insights have been made recently into the signalling mechanisms that induce G2-arrested oocytes to resume and complete the meiotic cell cycle.

PMID:
11063930
DOI:
10.1016/s0955-0674(00)00150-2
[Indexed for MEDLINE]

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