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J Assist Reprod Genet. 2000 Sep;17(8):405-8.

Routine blastocyst culture and transfer: 201 patients' experience.

Author information

1
Department of Obstetrics and Gynecology, China Medical College Hospital, Taichung, Taiwan.

Abstract

PURPOSE:

The purpose was to compare the outcomes between day-5 blastocyst and day-2 embryo transfers.

METHODS:

Infertile women who accepted the ovarian hyperstimulation and oocyte retrieval were divided: Group 1, day 2 embryo transfer, group 2, cultured to day 5 in serum-free sequential culture medium and transfer. Early embryo quality and growth, blastocyst formation and quality, implantation rate (IR) and pregnancy rates (PR) were detected.

RESULTS:

Total blastocyst formation rate was 49.4%. Better early embryo quality (days 2, 3) and higher day 3 blastomere number possess higher blastocyst formation rate. The IR for day 2 and day 5 embryos were 10.8% and 22.2%, respectively. The PR in both groups were comparable (37.3% vs. 41.8%).

CONCLUSIONS:

Blastocyst transfer has higher IR and comparable PR as those of day 2 embryo transfer. Early embryo qualities and day 3 blastomere number are useful in predicting the final blastocyst formation. Blastocyst formation rate is not related to maternal age, infertile causes, insemination methods, and early embryo number.

PMID:
11062848
PMCID:
PMC3455573
[Indexed for MEDLINE]
Free PMC Article
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