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Trends Biotechnol. 2000 Nov;18(11):449-55.

Frontiers in chemical genetics.

Author information

1
Whitehead Institute for Biomedical Research, Nine Cambridge Center, MA 02142, USA. stockwell@wi.mit.edu

Abstract

New methods enable the identification of compounds that both induce a specific cellular state and lead to identification of proteins that regulate that state. Together, developments in three critical areas: chemical diversity, phenotype-based screening and target identification, enable the systematic application of this chemical genetic approach to almost any biological problem or disease process.

PMID:
11058785
[Indexed for MEDLINE]

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