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Curr Opin Microbiol. 2000 Oct;3(5):496-501.

Antimicrobial use and bacterial resistance.

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1
Medical College of Virginia, Richmond, Virginia 23298, USA.

Abstract

The current epidemic of bacterial resistance is attributed, in part, to the overuse of antibiotics. Recent studies have documented increases in resistance with over-use of particular antibiotics and improvements in susceptibility when antibiotic use is controlled. The most effective means of improving use of antibiotics is unknown. Comprehensive management programs directed by multi-disciplinary teams, computer-assisted decision-making, and antibiotic cycling have been beneficial in controlling antibiotic use, decreasing costs without impacting patient outcomes, and possibly decreasing resistance.

PMID:
11050449
[Indexed for MEDLINE]

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