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Curr Biol. 2000 Oct 5;10(19):R708-11.

Gene silencing: two faces of SIR2.

Author information

1
Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA. Dgottsch@fhcrc.org

Abstract

There are still many mysteries surrounding how silenced regions of the eukaryotic genome are created and maintained. But recent discoveries about the most evolutionarily conserved silencing protein, Sir2p, have provided new mechanistic insights into these processes.

PMID:
11050406
[Indexed for MEDLINE]
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