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Neuroimage. 2000 Nov;12(5):582-7.

Correlations in low-frequency BOLD fluctuations reflect cortico-cortical connections.

Author information

1
Department of Radiology, Indiana University School of Medicine, Indianapolis, Indiana, USA.

Abstract

Cross-correlation of low-frequency temporal fluctuations (<0.08 Hz) was used to correlate widely separated anatomic regions during continuous performance of a spatial working memory task. The regions of highest correlation to right-hemisphere dorsolateral prefrontal cortex correspond to the regions of largest baseline signal change in a conventional block-style functional MRI paradigm. Additionally, it is shown that the correlations between elements of the functional network increase during performance of a task that activates the network when compared to a task that does not directly stimulate the functionally connected network.

PMID:
11034865
DOI:
10.1006/nimg.2000.0654
[Indexed for MEDLINE]

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