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Am J Infect Control. 2000 Oct;28(5):347-51.

Microbiologic contamination study of nebulizers after aerosol therapy in patients with cystic fibrosis.

Author information

1
Rouen University Hospital, France.

Abstract

BACKGROUND:

To evaluate the contamination of delivery systems after an aerosol therapy session in patients with cystic fibrosis who have chronic Pseudomonas aeruginosa infection.

METHODS:

Fifty-three patients with cystic fibrosis were enrolled in the study from March 1996 to June 1997. All patients were age 7 years or older and had P aeruginosa infection. They also had been treated with recombinant deoxyribonuclease and were capable of producing sputum for culture.

RESULTS:

Nine devices were excluded for the study. A total of 44 nebulizers were included: 37 from patients with P aeruginosa colonization with a count of 10(6) colony-forming units/mL or more and 7 with a count of between 10(5) colony-forming units/mL and 10(6) colony-forming units/mL.

CONCLUSION:

This study demonstrates that in the absence of cleaning, nebulizers of patients with cystic fibrosis who are infected with P aeruginosa are likely to be contaminated by a pathogenic flora.

PMID:
11029133
DOI:
10.1067/mic.2000.110214
[Indexed for MEDLINE]

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