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J Infect. 2000 Sep;41(2):176-8.

Medical treatment of a pacemaker endocarditis due to Candida albicans and to Candida glabrata.

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Service des Maladies Infectieuses et Tropicales, Hôpital de l'Archet, Route St Antoine de Ginestière, BP79, 06202 Nice, France.


We describe a case of pacemaker infection due to two fungal species: Candida albicans and C. glabrata. Transthoracic echocardiography showed a large vegetation on the intraventricular wires. Because of severe underlying diseases, surgery was believed to be contraindicated. The patient was treated using high dose of fluconazole, resulting in clinical improvement and negative blood cultures. However, 2 months later, the patient underwent a fatal stroke. At autopsy, a large vegetation was found only all along the wires. Postmortem culture of the infected material was positive for both C. albicans and C. glabrata.

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