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Diabetes Care. 2000 Oct;23(10):1556-62.

A review of the relationship between depression and diabetes in adults: is there a link?

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1
School of Psychology, Laval University, Sainte-Foy, Quebec, Canada.

Abstract

OBJECTIVE:

To review the support for two hypotheses concerning the interrelationship between depression and diabetes and to identify areas in which more research is needed.

RESEARCH DESIGN AND METHODS:

A review was conducted using primarily electronic databases. Articles relating to diabetes and depressive symptomatology, depressive disorder, and dysthymic disorder were selected. The study focuses mainly on adults with diabetes.

RESULTS:

The initial onset of major depressive disorder (MDD) seems to be independent of the onset of type 2 diabetes, but results remain equivocal for type 1 diabetes. However, in both type 1 and type 2 diabetes, diabetes-related psychological and physiological processes may be involved in the higher recurrence and longer duration of MDD and depressive symptomatology

CONCLUSIONS:

The hypotheses that the initial occurrence of clinically significant depression, MDD, results from either biochemical changes directly due to type 2 diabetes or its treatment or from the psychosocial demands imposed by the illness or its treatment do not seem to be supported. MDD in diabetic individuals represents a multidetermined phenomenon resulting from interactions between biologic and psychosocial factors. This interaction may increase the probability of developing type 2 diabetes in otherwise healthy individuals.

PMID:
11023152
[Indexed for MEDLINE]
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