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Haemophilia. 2000 Sep;6(5):504-7.

Combined factor V and VIII deficiency in Indian population.

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  • 1Institute of Immunohaematology (ICMR), 13th floor, New Multistoreyed Bldg, KEM Hospital campus, Parel Mumbai-400012, Mumbai.


The clinical and haematological heterogeneity in cases of the rare combined factor V and VIII deficiency has not been reported so far from India. Nine such cases belonging to five unrelated families have been analysed in the present study for the various haematological and clinical parameters. A very mild clinical presentation is seen in all these cases. The clinical manifestations, however, do not correlate with the plasma levels of these factors.

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