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Mol Gen Genet. 1975 Aug 5;139(2):167-76.

A temperature sensitive nonsense mutation affecting the synthesis of a major protein of Escherichia coli K12.

Abstract

A temperature sensitive nonsense (TSN) mutant of E. coli K12 has been isolated in which a major bacterial protein is not synthesized at 42 degrees C. This protein is found in the parental strain at 42 degrees C and in cells rendered temperature resistant due to the insertion of a number of different nonsense suppressors or the normal allele of the mutant locus.

PMID:
1101033
DOI:
10.1007/bf00264696
[Indexed for MEDLINE]
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