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Parasitol Today. 2000 Oct;16(10):427-33.

A brief illustrated guide to the ultrastructure of Plasmodium falciparum asexual blood stages.

Author information

1
Centre for Neuroscience, Hodgkin Building, Guy's, King's and St Thomas' Hospitals School of Basic Medical Science, KCL, Guy's Campus, SE1 1UL, London, UK. lawrence.bannister@umds.ac.uk

Abstract

Interpretation of the new information arising from the Plasmodium falciparum Genome Project requires a good working knowledge of the ultrastructure of the parasite; however many aspects of the morphology of this species remain obscure. Lawrence Bannister, John Hopkins and colleagues here give an illustrated overview of the three-dimensional (3-D) organization of the merozoite, ring, trophozoite and schizont stages of the parasite, based on available data that include 3-D reconstruc-tion from serial electron microscope sections. The review describes the chief organelles present in these stages, emphasizing the continuity of structure in addition to specialized, stage-specific features developed during the asexual erythrocytic cycle.

PMID:
11006474
[Indexed for MEDLINE]

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