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Parasitol Today. 2000 Oct;16(10):427-33.

A brief illustrated guide to the ultrastructure of Plasmodium falciparum asexual blood stages.

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Centre for Neuroscience, Hodgkin Building, Guy's, King's and St Thomas' Hospitals School of Basic Medical Science, KCL, Guy's Campus, SE1 1UL, London, UK.


Interpretation of the new information arising from the Plasmodium falciparum Genome Project requires a good working knowledge of the ultrastructure of the parasite; however many aspects of the morphology of this species remain obscure. Lawrence Bannister, John Hopkins and colleagues here give an illustrated overview of the three-dimensional (3-D) organization of the merozoite, ring, trophozoite and schizont stages of the parasite, based on available data that include 3-D reconstruc-tion from serial electron microscope sections. The review describes the chief organelles present in these stages, emphasizing the continuity of structure in addition to specialized, stage-specific features developed during the asexual erythrocytic cycle.

[Indexed for MEDLINE]

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