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Nature. 2000 Sep 14;407(6801):242-8.

Vascular-specific growth factors and blood vessel formation.

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1
Regeneron Pharmacueticals, Inc., Tarrytown, New York 10591, USA.

Abstract

A recent explosion in newly discovered vascular growth factors has coincided with exploitation of powerful new genetic approaches for studying vascular development. An emerging rule is that all of these factors must be used in perfect harmony to form functional vessels. These new findings also demand re-evaluation of therapeutic efforts aimed at regulating blood vessel growth in ischaemia, cancer and other pathological settings.

PMID:
11001067
DOI:
10.1038/35025215
[Indexed for MEDLINE]
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