Format

Send to

Choose Destination
See comment in PubMed Commons below
Trends Cell Biol. 2000 Oct;10(10):415-9.

Rho family GTPases: more than simple switches.

Author information

1
Picower Institute for Molecular Research, 350 Community Drive, Manhasset, NY 11030, USA. msymons@picpower.edu

Abstract

Rho family GTPases control a large variety of biological processes. Cycling of Rho proteins between the GDP-bound and the GTP-bound state is controlled by several classes of regulatory proteins. In this review, we discuss the signal-transduction mechanisms that control these regulators. We will emphasize the subcellular localization of Rho GTPases and their regulatory proteins and the role of GTP hydrolysis in signal transmission.

PMID:
10998597
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center