Format

Send to

Choose Destination
Chest. 2000 Sep;118(3):604-9.

MRI and CT in the differential diagnosis of pleural disease.

Author information

1
Klinik und Poliklinik für Strahlenheilkunde, Charité Virchow-Klinikum, Humboldt Universitat zu Berlin, Germany.

Abstract

STUDY OBJECTIVE:

To explore the role of MRI in the differential diagnosis of pleural disease.

PATIENTS:

Forty-two patients with pleural disease were included.

METHOD:

Retrospective study. All patients were examined with both CT and MRI. The morphologic features of pleural lesions and magnetic resonance signal intensity on T1-weighted, T2-weighted, and contrast-enhanced T1-weighted images were evaluated.

RESULTS:

Mediastinal pleural involvement, circumferential pleural thickening, nodularity, irregularity of pleural contour, and infiltration of the chest wall and/or diaphragm were most suggestive of a malignant cause both on CT and MRI. Pleural calcification on CT was suggestive of a benign cause. Contrary to what has been previously reported in the literature, neither on CT nor on MRI, pleural thickness >1 cm revealed significant difference between malignant and benign pleural disease (p>0.05, chi(2) test). High signal intensity in relation to intercostal muscles on T2-weighted and/or contrast-enhanced T1-weighted images was significantly suggestive for a malignant disease. Using morphologic features in combination with the signal intensity features, MRI had a sensitivity of 100% and a specificity of 93% in the detection of pleural malignancy.

CONCLUSION:

When signal intensity and morphologic features are assessed, MRI is more useful and therefore superior to CT in differentiation of malignant from benign pleural disease.

PMID:
10988179
DOI:
10.1378/chest.118.3.604
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center