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Curr Opin Struct Biol. 2000 Aug;10(4):443-7.

beta-Barrel membrane proteins.

Author information

1
Institut für Organische Chemie und Biochemie, Freiburg im Breisgau, Germany. schulz@bio.chemie.uni-freiburg.de

Abstract

beta-Barrel proteins are found in the outer membranes of bacteria, mitochondria and chloroplasts. The presently known sizes range from small eight-stranded to large twenty-two-stranded beta barrels existing as monomers and oligomers. Their functions are as diverse as active ion transport, passive nutrient intake, membrane anchors, membrane-bound enzymes and defense against attack proteins. Of further interest are the folding process, the crystallization, the observed limited structural diversity and the manifold channel engineering options of these beta-barrel proteins.

PMID:
10981633
DOI:
10.1016/s0959-440x(00)00120-2
[Indexed for MEDLINE]

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