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Curr Opin Genet Dev. 2000 Oct;10(5):529-35.

Genetic control of cell size.

Author information

1
Zoologisches Institut, Universität Zürich, Winterthurerstrasse 190, CH-8057, Zürich, Switzerland.

Abstract

Over the past 25 years, the genetic control of cell size has mainly been addressed in yeast, a single-celled organism. Recent insights from Drosophila have shed light on the signalling pathways responsible for adjusting and maintaining cell size in metazoans. Evidence is emerging for a signalling cascade conserved in evolution that links external nutrient sources to cell size.

PMID:
10980431
DOI:
10.1016/s0959-437x(00)00123-4
[Indexed for MEDLINE]

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