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Curr Opin Biotechnol. 2000 Aug;11(4):396-401.

Measuring gene expression by quantitative proteome analysis.

Author information

1
Department of Molecular Biotechnology, University of Washington, Seattle 98195-7730, USA. gygi@u.washington.edu

Abstract

Proteome analysis is most commonly accomplished by the combination of two-dimensional gel electrophoresis for protein separation, visualization, and quantification and mass spectrometry for protein identification. Over the past year, exceptional progress has been made towards developing a new technology base for the precise quantification and identification of proteins in complex mixtures, that is, quantitative proteomics.

PMID:
10975460
DOI:
10.1016/s0958-1669(00)00116-6
[Indexed for MEDLINE]

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