Abstract
A patient with the clinical features of dermatitis herpetiformis and the histological features of pemphigus, subcorneal dermatosis and dermatitis herpetiformis did not respond to treatment with pyridine or sulfones. Systemic steroids and azothioprine were effective. Immunofluorescence studies demonstrated circulating pemphigus antibodies and IgG bound in vivo in the intercellular spaces of the epidermis.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Abscess / pathology
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Acantholysis / pathology
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Aged
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Binding Sites, Antibody
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Biopsy
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Dermatitis Herpetiformis / diagnosis*
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Dermatitis Herpetiformis / immunology
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Dermatitis Herpetiformis / pathology
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Female
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Fluorescent Antibody Technique
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Humans
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Immunoglobulin G / metabolism
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Male
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Pemphigus / diagnosis*
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Pemphigus / immunology
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Pemphigus / pathology