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Eur J Biochem. 2000 Sep;267(18):5657-64.

A tribute to sulfur.

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Institute for Enzyme Research and Department of Biochemistry, College of Agricultural and Life Sciences, University of Wisconsin-Madison, 53705-4098, USA.


Recent progress in a number of areas of biochemistry and biology has drawn attention to the critical importance of sulfur in the biosynthesis of vital cofactors and active sites in proteins, and in the complex reaction mechanisms often involved. This brief review is intended as a broad overview of this currently rapidly moving field of sulfur biochemistry, for those who are interested or are involved in one or the other aspect of it, a synopsis by one who has stumbled into this field from several directions in the course of time. Only for iron are metal-sulfur relationships discussed in detail, as the iron-sulfur subfield is one of the most active areas.

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