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Curr Opin Neurol. 2000 Aug;13(4):431-6.

Prevention and therapeutic strategies for levodopa-induced dyskinesias in Parkinson's disease.

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Clinical Investigation Centre, University Hospital, Toulouse, France.


Levodopa-induced dyskinesias represent a major shortcoming of Parkinson's disease management, and its pharmacological treatment is generally unsatisfactory. However, the conclusive demonstration of the benefits associated with early prescription of a dopamine agonist, the antidyskinetic properties of 'old' antiparkinsonian compounds such as amantadine, and the striking results of functional stereotatic neurosurgery are extremely important advances for the treatment of levodopa-induced dyskinesias.

[Indexed for MEDLINE]

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