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Int J Med Microbiol. 2000 Jul;290(3):289-92.

Decontamination of a Mycoplasma-infected Chlamydia pneumoniae strain by pulmonary passage in SCID mice.

Author information

1
Department of Medical Microbiology and Hygiene, University of Ulm, Germany. andreas.essig@medizin.uni-ulm.de

Abstract

We describe a procedure to eliminate contaminating Mycoplasma from Chlamydia pneumoniae (C. pneumoniae) cultures by pulmonary passage in severe combined immunodeficiency mice (SCID). Four weeks after experimental infection only C. pneumoniae could be cultured from the lungs of the infected animals while Mycoplasma could not be detected any longer, as shown by PCR, culture and transmission electron microscopy (TEM).

PMID:
10959732
DOI:
10.1016/S1438-4221(00)80130-7
[Indexed for MEDLINE]

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