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Eur J Cancer. 2000 Aug;36(13 Spec No):1640-8.

Transcriptional regulation of cell invasion: AP-1 regulation of a multigenic invasion programme.

Author information

1
The Beatson Institute for Cancer Research, CRC Beatson Laboratories, Garscube Estate, Switchback Road, Bearsden, G61 1BD, Glasgow, UK. b.ozanne@beatson.gla.ac.uk

Abstract

The focus of this review will be on the regulation of the multigenic invasion programme by activator protein-1 (AP-1). Investigation of AP-1-regulated gene expression in transformed cells can be used to identify the genes in the multigenic invasion programme and to validate them as targets for diagnosis or therapy.

PMID:
10959050
DOI:
10.1016/s0959-8049(00)00175-1
[Indexed for MEDLINE]

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