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Semin Neonatol. 2000 Aug;5(3):231-41.

Perinatal complications associated with maternal tobacco use.

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Division of Maternal Fetal Medicine, Department of Obstetrics, Gynaecology and Reproductive Sciences, University of Texas, Houston Medical School, Houston, TX 77030, USA.


The use of tobacco products by pregnant women is associated with placenta previa, abruptio placentae, premature rupture of the membranes, preterm birth, intrauterine growth restriction and sudden infant death syndrome. Approximately 15-20% of women smoke during pregnancy. It has been suggested that smoking is responsible for 15% of all preterm births, 20-30% of all infants of low birthweight, and a 150% increase in overall perinatal mortality. Cigarette smoking is one of the most important and modifiable risk factors associated with adverse perinatal outcomes.

[Indexed for MEDLINE]

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