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Phys Med Biol. 2000 Jul;45(7):1741-54.

Monte Carlo dose computation for IMRT optimization.

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  • 1Abt. Medizinische Physik, Radiologische Uniklinik, Universität Tübingen, Germany.


A method which combines the accuracy of Monte Carlo dose calculation with a finite size pencil-beam based intensity modulation optimization is presented. The pencil-beam algorithm is employed to compute the fluence element updates for a converging sequence of Monte Carlo dose distributions. The combination is shown to improve results over the pencil-beam based optimization in a lung tumour case and a head and neck case. Inhomogeneity effects like a broader penumbra and dose build-up regions can be compensated for by intensity modulation.

[PubMed - indexed for MEDLINE]
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