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Exp Nephrol. 2000 Jul-Oct;8(4-5):226-34.

Immune recognition of glomerular antigens.

Author information

1
Department of Clinical and Surgical Sciences (Internal Medicine), University of Edinburgh, UK.richard.phelps@ed.ac.uk

Abstract

Autoimmunity is thought to cause most varieties of glomerulonephritis including membranous nephropathy, minimal-change nephropathy, Goodpasture's disease and possibly IgA nephropathy. Much effort has been and is directed at understanding the mechanisms of immune system driven inflammation and of the consequent renal injury and repair or scarring. The purpose of this article is to focus attention on the way the immune system recognizes kidney autoantigens, a process that must be a pivotal in the initiation of autoimmune kidney disease.

PMID:
10940721
DOI:
10.1159/000020673
[Indexed for MEDLINE]

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