Format

Send to

Choose Destination
J Ethnopharmacol. 2000 Aug;71(3):443-7.

Anti-inflammatory and analgesic activity of Biebersteinia multifida DC. root extract.

Author information

1
Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, 14155-6451, Tehran, Iran. farsam@sina.tums.ac.ir

Abstract

The root of Biebersteinia multifida DC (Geraniaceae), a native plant of Iran, has been used topically for the treatment of musculoskeletal disorders as a folk medicine. The anti-inflammatory and analgesic effects of the root extract were studied using carrageenan induced edema and formalin tests. A similar activity was seen between Biebersteinia multifida root extract (10 mg/kg; i.p.) and indomethacin (4 mg/kg; i.p.) in carrageenan test. The results of formalin test showed the analgesic activity of the root extract (50 mg/kg; i.p.) was comparable with morphine (10 mg/kg; i.p.) at the first phase of formalin test. Furthermore, the probable ulcerogenic activity of the root extract was also studied. The extract did not show any ulcerogenic effect at anti-inflammatory doses (10 mg/kg; p.o.).

PMID:
10940581
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center