Format

Send to

Choose Destination
Nat Struct Biol. 2000 Aug;7(8):648-52.

Structure of the DNA binding domain of E. coli SSB bound to ssDNA.

Author information

1
Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, Campus Box 8231, 660 S. Euclid Ave., Saint Louis, Missouri 63110, USA.

Abstract

The structure of the homotetrameric DNA binding domain of the single stranded DNA binding protein from Escherichia coli (Eco SSB) bound to two 35-mer single stranded DNAs was determined to a resolution of 2.8 A. This structure describes the vast network of interactions that results in the extensive wrapping of single stranded DNA around the SSB tetramer and suggests a structural basis for its various binding modes.

PMID:
10932248
DOI:
10.1038/77943
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Nature Publishing Group
Loading ...
Support Center