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Anticancer Res. 2000 May-Jun;20(3B):1905-12.

Genetic alterations in human prostate cancer: a review of current literature.

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1
Department of Cancer Biology, University of Texas M. D. Anderson Cancer Center, Houston 77030, USA.

Abstract

We review the literature dealing with genetic alterations in human prostate cancer. We also discuss genetic predisposition and the roles of various proto-oncogenes and tumor-suppressor genes in prostate cancer initiation, progression, and metastasis. The role of telomere dynamics in prostate cancer metastasis and the induction of apoptosis is also briefly discussed.

PMID:
10928125
[Indexed for MEDLINE]
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