Format

Send to

Choose Destination
Stem Cells. 2000;18(4):295-300.

Isolation and characterization of neural stem cells from the adult human olfactory bulb.

Author information

1
Laboratory of Neuropharmacology, National Neurological Institute C. Besta, Milan, Italy.

Abstract

We have recently isolated stem cells deriving from the olfactory bulbs of adult patients undergoing particularly invasive neurosurgery. After improving our experimental conditions, we have now obtained neural stem cells according to clonal analysis. The cells can be expanded, established in continuous cell lines and differentiated into the three classical neuronal phenotypes (neurons, astrocytes, and oligodendrocytes). Also, after exposition to leukemia inhibitory factor, we are able to improve the number of neurons, an ideal biological source for transplantation in various neurodegenerative disorders.

PMID:
10924096
DOI:
10.1634/stemcells.18-4-295
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center