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Trends Biochem Sci. 2000 Aug;25(8):388-91.

Signaling networks linking integrins and rho family GTPases.

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1
Dept of Vascular Biology, The Scripps Research Institute, La Jolla, CA 92037, USA. schwartz@scripps.edu

Abstract

Integrins and Rho family GTPases function coordinately to mediate adhesion-dependent events in cells. Recently, it has also become apparent that integrins regulate Rho GTPases and vice versa. Integrins and GTPases might therefore be organized into complex signaling cascades that regulate cell behavior.

PMID:
10916159
[Indexed for MEDLINE]
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