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Acc Chem Res. 2000 Jul;33(7):503-10.

Elucidating a biological role for chromium at a molecular level.

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1
Department of Chemistry and Coalition for Biomolecular Products, The University of Alabama, Tuscaloosa, Alabama 35487-0336, USA.

Abstract

Chromium is an essential trace element for mammals and is required for maintenance of proper carbohydrate and lipid metabolism. However, elucidating its function at a molecular level has proved to be problematic. Recent research has revealed that the chromium-binding oligopeptide chromodulin may play a unique role in the autoamplification of insulin signaling. Attempts to develop chromium-containing nutritional supplements and therapeutics are described.

PMID:
10913239
[Indexed for MEDLINE]
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