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Mech Ageing Dev. 2000 Jun 20;115(3):199-207.

Program for testing biological interventions to promote healthy aging.

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  • 1National Institute on Aging, Biology of Aging Program, 7201 Wisconsin Avenue, Gateway Building, Suite 2C231, Bethesda, MD 20892, USA.


The National Institute on Aging (NIA) sponsored a workshop on September, 1999 to discuss the feasibility of establishing a program to evaluate potential intervention strategies to decelerate the rate of aging in mammals. The ultimate goal is to identify promising interventions in animals that might lead to clinical trials in humans. The participants discussed various animal models, biological endpoints and possible structure of such a program. The ability to implement such a program will require a decision by NIA staff about whether the anticipated benefits to be derived from identification of effective interventions under well controlled conditions in an animal model, in this case the mouse, would justify the anticipated cost of the testing program.

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