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Structure. 2000 Jul 15;8(7):R137-42.

Luxury accommodations: the expanding role of structural plasticity in protein-protein interactions.

Author information

1
Center for Advanced Research in Biotechnology, University of Maryland, Biotechnology Institute, Rockville, MD 20850, USA.

Abstract

The recognition of multiple ligands at a single molecular surface is essential to many biological processes. Conformational flexibility has emerged as a compelling strategy for association at such convergent binding sites. Studies over the past few years have brought about a greater understanding of the role that protein plasticity might play in protein-protein interactions.

PMID:
10903952
DOI:
10.1016/s0969-2126(00)00167-2
[Indexed for MEDLINE]
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