Format

Send to

Choose Destination
Curr Opin Immunol. 2000 Aug;12(4):413-8.

Cytokines and T cells in host defense.

Author information

1
Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. chunter@phl. vet.upenn.edu

Abstract

Soluble and cell-bound ligands profoundly influence the differentiative fate of lymphocytes during an immune response. Recent advances have been made in understanding the role of cytokine signals and costimulatory signals in the regulation of T cell responses associated with resistance or susceptibility to infection. There has also been recent progress in defining the requirements for the generation and maintenance of immunologic memory, a critical component of adaptive immunity.

PMID:
10899023
DOI:
10.1016/s0952-7915(00)00110-2
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center