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Magn Reson Med. 2000 Jul;44(1):162-7.

Image-based method for retrospective correction of physiological motion effects in fMRI: RETROICOR.

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1
Department of Radiology, Stanford University School of Medicine, Center for Advanced MR Technology at Stanford, Stanford, California, USA. gary@s-word.stanford.edu

Abstract

Respiration effects and cardiac pulsatility can induce signal modulations in functional MR image time series that increase noise and degrade the statistical significance of activation signals. A simple image-based correction method is described that does not have the limitations of k-space methods that preclude high spatial frequency correction. Low-order Fourier series are fit to the image data based on time of each image acquisition relative to the phase of the cardiac and respiratory cycles, monitored using a photoplethysmograph and pneumatic belt, respectively. The RETROICOR method is demonstrated using resting-state experiments on three subjects and compared with the k-space method. The method is found to perform well for both respiration- and cardiac-induced noise without imposing spatial filtering on the correction. Magn Reson Med 44:162-167, 2000.

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