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Methods Inf Med. 2000 Jun;39(2):179-82.

Integration of high resolution EEG and functional magnetic resonance in the study of human movement-related potentials.

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Department of Human Physiology, University of Rome La Sapienza, Rome, Italy [corrected].

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  • Methods Inf Med 2000 Aug;39(3):277.


Cortical sources of human movement-related potentials (i.e. unilateral finger extension) were modeled using functional magnetic resonance imaging (fMR) data as a constraint of a linear inverse source estimation from highly sampled (128 channels) EEG data. Remarkably, this estimation was performed within realistic subject's MR-constructed head models by boundary element techniques. An appropriate figure of merit served to set the optimal amount of fMR constraints. With respect to standard linear inverse source estimates, fMR-constrained ones presented increased spatial detail and provided a more reliable timing of activation in bilateral sensorimotor cortical regions of interest.

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