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J Antimicrob Chemother. 2000 Jul;46(1):133-6.

Antibiotic susceptibility and mechanisms of beta-lactam resistance in 1310 strains of pseudomonas aeruginosa: a French multicentre study (1996).

Author information

1
Hôpital d'Instruction des Armées Bégin, 69 Avenue de Paris, 94163 St Mandé, France. beginbio@club-internet.fr

Abstract

A total of 1310 consecutive strains of Pseudomonas aeruginosa were collected in 11 French hospitals in 1996. The percentages of susceptible isolates measured by the agar dilution method were: ticarcillin (53%), piperacillin (69%) (MIC 16 mg/L), ceftazidime (77%), cefepime (55%), cefpirome (40%), aztreonam (57.5%), imipenem (81.5%) (MIC 4 mg/L), amikacin (64.5%) (MIC 8 mg/L) and ciprofloxacin (58%) (MIC 1 mg/L). Resistance to beta-lactams was linked to the production of transferable beta-lactamases (30%), overproduction of cephalosporinase (29%) and to non-enzymic mechanisms (38%).

PMID:
10882703
DOI:
10.1093/jac/46.1.133
[Indexed for MEDLINE]

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