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Curr Opin Lipidol. 2000 Jun;11(3):229-34.

Triglyceride synthesis: insights from the cloning of diacylglycerol acyltransferase.

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Gladstone Institutes of Cardiovascular Disease, San Francisco, CA 94141-9100, USA.


Although the biochemistry of triglyceride synthesis has been studied for decades, an understanding of the molecular processes involved has been lacking. The recent cloning of a gene encoding acyl coenzyme A : diacylglycerol acyltransferase, an enzyme that catalyses the final step in triglyceride synthesis, has opened this area to molecular investigation and has begun to provide new insights into triglyceride metabolism.

[Indexed for MEDLINE]

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