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Virchows Arch. 2000 May;436(5):502-5.

Primary lumbosacral Wilms tumour associated with occult spinal dysraphism.

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Department of Pathology, University of Natal Medical School, Durban, South Africa.


A 4-year-old child presenting with sudden-onset paraplegia and a sacral tumour in association with spina bifida occulta is reported. There were no stigmata of spinal dysraphism at birth. Imaging studies confirmed a sacral tumour with extradural extension up to T10 and spinal dysraphism. The histological features of the extradural and sacral components of the tumour were consistent with a Wilms tumour. The differential diagnosis included a primary sacral teratoma containing Wilms tumour elements or a primary extrarenal Wilms tumour arising in association with a spinal dysraphism. There was no clinical response to chemotherapy or radiotherapy.

[Indexed for MEDLINE]

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