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Clin Infect Dis. 2000 Jun;30 Suppl 3:S243-6.

Immunologic diagnosis of tuberculosis.

Author information

1
Public Health Research Institute, New York, NY 10016, USA. gennaro@phri.nyu.edu

Abstract

Evaluation of new vaccines against tuberculosis requires diagnostic tools for accurately identifying asymptomatic individuals infected with Mycobacterium tuberculosis and persons with active tuberculosis. This article discusses limitations of current methods for the immunologic diagnosis of latent infection and active disease and presents novel approaches to developing skin tests and serodiagnostic assays based on "cocktails" of multiple antigens of M. tuberculosis.

PMID:
10875791
DOI:
10.1086/313868
[Indexed for MEDLINE]

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