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Chem Biol. 2000 Jun;7(6):R127-32.

Resisting resistance: new chemical strategies for battling superbugs.

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1
Department of Biochemistry, Antimicrobial Research Centre, McMaster University, ON, L8N 3Z5, Canada. wrightge@fhs.csu.mcmaster.ca.

Abstract

As microbes become increasingly resistant to antibiotics, and in many cases to several drugs simultaneously, the search is on to find new therapies. One method to combat resistance is to use inhibitors of resistance mechanisms to potentiate existing antibiotics. Recent efforts are encouraging and highlight the importance of research at the chemistry-microbiology interface in developing new approaches to tackle resistance.

PMID:
10873842
[Indexed for MEDLINE]
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